XI Yumeng
Assistant Professor, NUS Presidential Young Professorship
Postdoc, University of California, Santa Barbara, 2020-2022; Ph.D., University of California, Berkeley, 2019; M.S., West Virginia University, 2014; B.S., Peking University, 2011.
Contact Information:
Office: S9-14-01B
Tel: (65)-6601-1840
Fax: (65)-6779-1691
Email: yumengxi@nus.edu.sg
Research
Recognition and Achievements
- NUS Presidential Young Professorship, NUS, 2022
- Reaxys PhD Prize Finalist, 2019
- Chinese Government Award for Outstanding Self-Financed Students Abroad, 2019
- Bristol-Myers Squibb Graduate Fellowship in Synthetic Organic Chemistry, 2018-2019
- Genentech Graduate Student Symposium in Chemical Research, 2018
- John Stauffer Fellowship in Chemistry, UC Berkeley, 2014
- John R. Conard Fellowship, West Virginia University, 2013
Research Interests
The research in the Xi group at NUS will bridge synthetic organic chemistry, polymer science, organometallics, and computational chemistry to solve challenging problems in catalysis, energy, sustainability, and health.
- We invent unconventional strategies to build and modify small organic molecules using transition-metal, organo, and photoredox catalysis.
- We develop methods to synthesize macromolecules with precise control of composition, sequence, stereochemistry, and architecture,
- We seek novel and effective solutions to tackle challenges in sustainable polymers.
- We will collaborate with experts in the fields of catalysis, energy, electrochemistry, and biomedicine to prepare materials for real-world applications.
We are constantly seeking self-driven, creative, and dedicated researchers to join our group! Interested postdoctoral fellows, graduate students, undergraduate students, and research assistants are encouraged to contact Dr. Xi directly. Please visit Dr. Xi’s personal website for further information.
Teaching Contributions in AY2023/2024
- CM3121 – Advanced Organic Chemistry
Representative Publications
- Ma. S.; Fan, F.; Day, C. S.; Xi, Y.; Hartwig, J. F., Remote Hydroamination of Disubstituted Alkenes by a Combination of Isomerization and Regioselective N–H Addition. J. Am. Chem. Soc., 2023, 145, 3875.
- Ma, S.; Xi, Y.; Fan, H.; Hartwig, J. F., Enantioselective hydroamination of unactivated terminal alkenes. Chem, 2022, 8, 532.
- Geng, Z.; Shin, J. J.; Xi, Y.; Hawker, C. J., Click Chemistry Strategies for the Accelerated Synthesis of Functional Macromolecules. J. Polym. Sci., 2021, 59, 963.
- Xi, Y.; Ma, S.; Hartwig, J. F., Catalytic asymmetric addition of an amine N–H bond across internal alkenes. Nature, 2020, 588, 254.
- Xi, Y.; Su, B.; Qi, X.; Pedram, S.; Liu, P.; Hartwig, J. F., Application of Trimethylgermanyl-Substituted Bisphosphine Ligands with Enhanced Dispersion Interactions to Copper-Catalyzed Hydroboration of Disubstituted Alkenes. J. Am. Chem. Soc., 2020, 142, 18213.
- Xi, Y.; Hartwig, J. F., Mechanistic Study of Copper-Catalyzed Asymmetric Hydroboration of Alkenes. J. Am. Chem. Soc., 2017, 139, 12758.
- Xi, Y.; Hartwig, J. F., Diverse Asymmetric Hydrofunctionalization of Aliphatic Internal Alkenes Through Catalytic Regioselective Hydroboration. J. Am. Chem. Soc., 2016, 138, 6703.
- Xi, Y.; Butcher, T. W.; Zhang, J.; Hartwig, J. F., Regioselective, Asymmetric Formal Hydroamination of Unactivated Internal Alkenes. Angew. Chem. Int. Ed., 2016, 55, 776.
- Xi, Y.; Su, Y.; Yu, Z.; Dong, B.; McClain, E. J.; Lan, Y.; Shi, X., Chemoselective Carbophilic Addition of α-Diazoesters through Ligand-Controlled Gold Catalysis. Angew. Chem. Int. Ed., 2014, 53, 9817.
- Xi, Y.; Dong, B.; McClain, E. J.; Wang, Q.; Gregg, T. L.; Akhmedov, N. G.; Petersen, J. L.; Shi, X., Gold-Catalyzed Intermolecular C-S Bond Formation: Efficient Synthesis of α-Substituted Vinyl Sulfone. Angew. Chem. Int. Ed., 2014, 53, 4647.
