HOANG Truong Giang
Senior Lecturer
Ph.D., University of Minnesota, Twin Cities, USA, 2012; B.Sc. Hons. (First Class), National University of Singapore, 2004.
Contact Information:
Office: S5-05-06
Tel: (65)-6601-7393
Fax: (65)-6779-1691
Email: chmhoan@nus.edu.sg
Research
Recognition and Achievements
- Chair of the Department Outreach Committee (July 2021 – present)
- Co-chair of the Department Teaching Evaluation Committee (July 2021 – present)
- Coordinator of the NUS Chemistry Internship Programme 2019-2021
- Mentor of the Singapore International Chemistry Olympiad Team 2013, 2019-2021
- Member of the Scientific Committee for the Singapore Junior Chemistry Olympiad 2018 and 2019
- Faculty Teaching Excellence Award 2014/2015, AY2020/2021
Research Interests
We are interested in designing new platforms to enhance chemistry undergraduate laboratory education. Working in the area of organic and medicinal chemistry, we incorporate guided inquiry pedagogy and the modern concept of green chemistry into the new experiments.
Research Highlight
New experiments were designed based on the Diels–Alder reaction of 2,3,4,5-tetraphenylcyclopentadienone, which is synthesized prior to or in a one-pot reaction, with styrene. Students are presented with three possible products, the endo and exo diastereomers and the decarbonylated product. Both versions of the synthesis introduce students to two important and atom economical reactions, use of the Karplus relationship for 1H NMR interpretation, and the power of X-ray crystallography for molecular structure determination.
Teaching Contributions AY2022/2023
- CM2122 Organic Chemistry in Life and Medicine (lab)
- CM3222 Organic Reaction Mechanisms
- CM4274 The Art and Methodology in Total Synthesis
- CM5103 Industry Practices in Chemistry (Module Coordinator)
- CM5104 Entrepreneurship Intellectual Property
Representative Publications
- Ong J. Y; Chang S. C.; Hoang T. G., Empowering Students to Design and Evaluate Synthesis Procedures: a Sonogashira Coupling Project for Advanced Teaching Lab. Chem. Educ. 2018, 95, 1078–1081.
- Serratore N. A.; Anderson C. B.; Frost G. B.; Hoang T. G.; Underwood S. J.; Gemmel P. M.; Hardy M. A.; Douglas C. J., Integrating Metal-Catalyzed C–H and C–O Functionalization To Achieve Sterically Controlled Regioselectivity in Arene Acylation. J. Am. Chem. Soc. 2018, 140, 10025-10033.
- Hoang T. G.; Walsh D. J.; McGarry K. A.; Anderson C. B.; Douglas C. J., Development and Mechanistic Study of Quinoline-Directed Acyl C–O Bond Activation and Alkene Oxyacylation Reactions. J. Org. Chem., 2017, 82, 2972–2983.
- Hoang, G. T.; Kubo, T.; Young, V. G.; Kautzky, J. A.; Wissinger, J. E. Illustrating the Utility of X-ray Crystallography for Structure Elucidation through a Tandem Aldol Condensation/Diels-Alder Reaction Sequence. J. Chem. Educ. 2015, 92, 1381-1384.
- Hoang, G. T.; Pan, Z. D.; Brethorst, J. T.; Douglas, C. J. Intramolecular Oxyacylation of Alkenes Using a Hydroxyl Directing Group. J. Org. Chem. 2014, 79, 11383-11394.
- Hoang, G. A. T.; Reddy, V. J.; Nguyen, H. H. K.; Douglas, C. J. Insertion of an Alkene into an Ester: Intramolecular Oxyacylation Reaction of Alkenes through Acyl C-O Bond Activation. Angew. Chem. Int. Ed. 2011, 50, 1882-1884. [Selected by the Editorial Board as a “Hot Paper”].
